Patient Stories & Clinical Evidence
Real Experiences. Real Relief.
Hear From People Who Completed the SideBy Care Program
Real Experiences. Real Relief.
Hear From People Who Completed the SideBy Care Program
Real Experiences. Real Relief.
Hear From People Who Completed the SideBy Care Program
SideBy Care Program Case Studies
SideBy Care Program Case Studies
SideBy Care Program Case Studies
Explore real-world examples of patients who completed the SideBy Care Program and the outcomes they achieved.
Presurgical Optimization
Achieving 80% Improvement in GI and Mental Health
Presurgical Optimization
Achieving 80% Improvement in GI and Mental Health
Presurgical Optimization
Achieving 80% Improvement in GI and Mental Health
Clinical Optimization & Pregnancy
Managing Complex Life Transitions Through GI Stabilization
Clinical Optimization & Pregnancy
Managing Complex Life Transitions Through GI Stabilization
Clinical Optimization & Pregnancy
Managing Complex Life Transitions Through GI Stabilization
Integrated Behavioral + Nutrition Treatment
Impact on GI Symptom Severity & Patient Resilience
Integrated Behavioral + Nutrition Treatment
Impact on GI Symptom Severity & Patient Resilience
Integrated Behavioral + Nutrition Treatment
Impact on GI Symptom Severity & Patient Resilience
Research & Evidence
The SideBy Care Program is grounded in evidence supporting the integration of behavioral health and nutrition into digestive care.
Explore selected research and clinical guidance related to disorders of gut-brain interaction (DGBIs), Crohn’s disease, and ulcerative colitis.
DGBIs & IBS
Behavioral + Nutrition Care for IBS
Behavioral and Diet Therapies in Integrated Care for Patients With Irritable Bowel Syndrome Gastroenterology, 2021 | Review
Gastroenterology, 2021 | Review
Reviews the evidence for integrating behavioral therapy, nutrition, and medical treatment in IBS care.
Behavioral + Nutrition Care for IBS
Behavioral and Diet Therapies in Integrated Care for Patients With Irritable Bowel Syndrome
Gastroenterology, 2021 | Review
Reviews the evidence for integrating behavioral therapy, nutrition, and medical treatment in IBS care.
Behavioral + Nutrition Care for IBS
Behavioral and Diet Therapies in Integrated Care for Patients With Irritable Bowel Syndrome Gastroenterology, 2021 | Review
Gastroenterology, 2021 | Review
Reviews the evidence for integrating behavioral therapy, nutrition, and medical treatment in IBS care.
Gut-Brain Behavioral Treatment for DGBIs
A Rome Working Team Report on Brain-Gut Behavior Therapies for Disorders of Gut-Brain Interaction
Gastroenterology, 2022 | Expert Consensus
Examines the evidence and role of brain-gut behavioral therapies in treating disorders of gut-brain interaction.
Gut-Brain Behavioral Treatment for DGBIs
A Rome Working Team Report on Brain-Gut Behavior Therapies for Disorders of Gut-Brain Interaction
Gastroenterology, 2022 | Expert Consensus
Examines the evidence and role of brain-gut behavioral therapies in treating disorders of gut-brain interaction.
Gut-Brain Behavioral Treatment for DGBIs
A Rome Working Team Report on Brain-Gut Behavior Therapies for Disorders of Gut-Brain Interaction
Gastroenterology, 2022 | Expert Consensus
Examines the evidence and role of brain-gut behavioral therapies in treating disorders of gut-brain interaction.
Evidence-Based Treatment for IBS
ACG Clinical Guideline: Management of Irritable Bowel Syndrome
American Journal of Gastroenterology, 2021 | Clinical Guideline
American College of Gastroenterology guidance for the evidence-based diagnosis and treatment of IBS, including dietary and gut-directed psychotherapeutic approaches.
Evidence-Based Treatment for IBS
ACG Clinical Guideline: Management of Irritable Bowel Syndrome
American Journal of Gastroenterology, 2021 | Clinical Guideline
American College of Gastroenterology guidance for the evidence-based diagnosis and treatment of IBS, including dietary and gut-directed psychotherapeutic approaches.
Evidence-Based Treatment for IBS
ACG Clinical Guideline: Management of Irritable Bowel Syndrome
American Journal of Gastroenterology, 2021 | Clinical Guideline
American College of Gastroenterology guidance for the evidence-based diagnosis and treatment of IBS, including dietary and gut-directed psychotherapeutic approaches.
Remote CBT for IBS
Assessing Telephone-Delivered Cognitive-Behavioural Therapy and Web-Delivered CBT Versus Treatment as Usual in Irritable Bowel Syndrome (ACTIB)
Gut, 2019 | Randomized Controlled Trial
A large randomized trial evaluating telephone- and web-delivered CBT for people with IBS.
24-Month Follow-Up
Gut, 2019 | Randomized Controlled Trial
Reviews the evidence for integrating behavioral therapy, nutrition, and medical treatment in IBS care.
Remote CBT for IBS
Assessing Telephone-Delivered Cognitive-Behavioural Therapy and Web-Delivered CBT Versus Treatment as Usual in Irritable Bowel Syndrome (ACTIB)
Gut, 2019 | Randomized Controlled Trial
A large randomized trial evaluating telephone- and web-delivered CBT for people with IBS.
24-Month Follow-Up
Long-term follow-up examining whether benefits persisted two years after treatment.
Remote CBT for IBS
Assessing Telephone-Delivered Cognitive-Behavioural Therapy and Web-Delivered CBT Versus Treatment as Usual in Irritable Bowel Syndrome (ACTIB)
Gut, 2019 | Randomized Controlled Trial
A large randomized trial evaluating telephone- and web-delivered CBT for people with IBS.
24-Month Follow-Up
Gut, 2019 | Randomized Controlled Trial
Reviews the evidence for integrating behavioral therapy, nutrition, and medical treatment in IBS care.
Crohn’s Disease & Ulcerative Colitis (IBD)
Mental Health Across the IBD Journey
Psychiatric Risks Rise Before IBD Diagnosis
AGA GI & Hepatology News, 2026 | Research Summary
A nationwide study of more than 40,000 people with IBD found increased psychiatric risk beginning before diagnosis and continuing for years afterward—highlighting the importance of addressing mental health throughout the IBD journey.
Mental Health Across the IBD Journey
Psychiatric Risks Rise Before IBD Diagnosis
AGA GI & Hepatology News, 2026 | Research Summary
A nationwide study of more than 40,000 people with IBD found increased psychiatric risk beginning before diagnosis and continuing for years afterward—highlighting the importance of addressing mental health throughout the IBD journey.
Mental Health Across the IBD Journey
Psychiatric Risks Rise Before IBD Diagnosis
AGA GI & Hepatology News, 2026 | Research Summary
A nationwide study of more than 40,000 people with IBD found increased psychiatric risk beginning before diagnosis and continuing for years afterward—highlighting the importance of addressing mental health throughout the IBD journey.
Psychological Therapies in IBD
Efficacy of Psychological Therapies in People With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis
Systematic Review & Meta-Analysis
A review of randomized trials examining the effects of psychological therapies on quality of life, anxiety, depression, stress, and disease activity in people with IBD.
Psychological Therapies in IBD
Efficacy of Psychological Therapies in People With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis
Systematic Review & Meta-Analysis
A review of randomized trials examining the effects of psychological therapies on quality of life, anxiety, depression, stress, and disease activity in people with IBD.
Psychological Therapies in IBD
Efficacy of Psychological Therapies in People With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis
Systematic Review & Meta-Analysis
A review of randomized trials examining the effects of psychological therapies on quality of life, anxiety, depression, stress, and disease activity in people with IBD.
CBT + Quality of Life in IBD
Cognitive Behavioral Therapy for Inflammatory Bowel Disease: A Meta-Analysis of Randomized Controlled Trials
Systematic Review & Meta-Analysisournal of Gastroenterology, 2021 | Clinical Guideline
Examines the effects of cognitive behavioral therapy on quality of life, anxiety, and depression in people living with IBD.
CBT + Quality of Life in IBD
Cognitive Behavioral Therapy for Inflammatory Bowel Disease: A Meta-Analysis of Randomized Controlled Trials
Systematic Review & Meta-Analysisournal of Gastroenterology, 2021 | Clinical Guideline
Examines the effects of cognitive behavioral therapy on quality of life, anxiety, and depression in people living with IBD.
CBT + Quality of Life in IBD
Cognitive Behavioral Therapy for Inflammatory Bowel Disease: A Meta-Analysis of Randomized Controlled Trials
Systematic Review & Meta-Analysisournal of Gastroenterology, 2021 | Clinical Guideline
Examines the effects of cognitive behavioral therapy on quality of life, anxiety, and depression in people living with IBD.
Psychological Interventions for IBD
Psychological Interventions for Treatment of Inflammatory Bowel Disease
Cochrane, 2025 | Systematic Review
A comprehensive review of evidence evaluating psychological interventions for people living with inflammatory bowel disease.
Psychological Interventions for IBD
Psychological Interventions for Treatment of Inflammatory Bowel Disease
Cochrane, 2025 | Systematic Review
A comprehensive review of evidence evaluating psychological interventions for people living with inflammatory bowel disease.
Psychological Interventions for IBD
Psychological Interventions for Treatment of Inflammatory Bowel Disease
Cochrane, 2025 | Systematic Review
A comprehensive review of evidence evaluating psychological interventions for people living with inflammatory bowel disease.